高風英，女，1976年12月出生，博士，副研究員，畢業于上海海洋大學水產養殖專業，碩士研究生導師，國家特色淡水魚產業技術體系崗位科學家。主要從事魚類健康養殖及選育種研究。研究涉及魚類抗病選育及免疫相關基因的挖掘及功能分析等領域。先后主持國家現代農業產業技術體系項目、國家及省級重點研發計劃、國家自然科學基金、廣東省自然科學基金、廣東省科技計劃項目等9項；參與國家科技支撐計劃、廣東省漁業發展專項等科研項目10余項。近年在國內外期刊公開發表論文近100篇，其中，第1作者及通訊作者35篇（其中SCI論文21篇）。作為骨干獲得新品種2個；獲發明專利授權5件。獲水科院科技進步一等獎1項、二等獎1項，水科院科技進步三等獎1項，水科院大漁創新獎1項，廣東省農業技術推廣獎2項，范蠡科學技術獎二等獎1項。2013年獲得廣東省直機關“三八紅旗手”榮譽稱號。
聯系方式：
(1)電話：13662315839
(2)郵箱：fengyinggao2011@163.com
研究方向：魚類健康養殖及選育種
主持的重點項目（僅列重大項目5項）
1．國家特色淡水魚產業技術體系專項(CARS-46)：淡水鱸種質資源與品種改良崗位，2023～2025年，210萬。
2．國家重點研發計劃：羅非魚抗細菌感染的先天免疫機制(2018YFD0900302-9)，起止時間：2018年12月-2022年12月，46萬。
3．國家自然科學基金：尼羅羅非魚MHC I基因組區域標簽SNPs的挖掘及其在輔助抗病育種中的應用潛力探討(31402295)，起止時間：2015年1月-2017年12月, 25萬。
4．廣東省自然科學基金：DDX41和Sting基因信號轉導機制及其在抵御鏈球菌感染中的作用研究(2020A1515010883),起止時間：2019年-2022年，10萬。
5．廣東省科技計劃項目：尼羅羅非魚抗鏈球菌新品系培育技術研究(2016A020210022)，起止時間：2016年7月-2019年7月，15萬。
代表論文（僅列第一作者和通訊作者SCI論文）
1. Junjian Dong, Hetong Zhang, Ziyang Wang, Chengfei Sun,Fengying Gao*, Xing Ye*. High temperature exposure causes sexual dimorphism in immune responses against largemouth bass ranavirus (LMBV) inMicropterus salmoides. Aquaculture 592 (2024) 741239.通訊作者
2.Fengying Gao, Junjian Dong, Jiaxin Li, Zhilin Zhu, Hetong Zhang, Chengfei Sun*, Xing Ye. TLR21 is involved in the NF-κB and IFN-β pathways in largemouth bass (Micropterus salmoides) and interacts with TRIF but not with the Myd88 adaptor. Fish and Shellfish Immunology 151 (2024) 109734.第一作者
3. Qiuyue Zheng, Zhigang Liu, Chengfei Sun, Junjian Dong, Hetong Zhang, Xiaoli Ke*,Fengying Gao*, Maixin Lu. Molecular characterization, expression and functional analysis of TAK1, TAB1 and TAB2 in Nile tilapia (Oreochromis niloticus). Fish and Shellfish Immunology 145 (2024) 109359.通訊作者
4. Junjian Dong, Chengfei Sun, Yuanyuan Tian, Hetong Zhang, Zhigang Liu,Fengying Gao*, Xing Ye*. Genomic organization and gene evolution of two warm temperature acclimation proteins (Wap65s) ofMicropterus salmoidesand their responses to temperature and bacterial/viral infections. International Journal of Biological Macromolecules 227 (2023) 340-353.通訊作者
5. Hetong Zhang, Junjian Dong, Yunyun Yan, Shanshan Liu, Xing Ye,Fengying Gao*and Chengfei Sun*. Development of a Highly Permissive Mandarin Fish (Siniperca chuatsi) Kidney Cell Line for Mandarin Fish Ranavirus Using a Single-Cell Cloning Method. Cells. 2024, 13(1): 18.
6.Gao Feng-ying, Lu Mai-xin*, Wang Miao, Liu Zhi-gang, Ke Xiao-li, Zhang De-feng, Cao Jian-meng.Nile tilapia DNA sensor STING is involved in the IFN-β and AP-1 signaling pathways in the immune response dependent on DDX41. International Journal of Biological Macromolecules 225 (2023) 27-39.第一作者
7. Qiuyue Zheng,Fengying Gao*, Zhigang Liu, Chengfei Sun, Junjian Dong, Hetong Zhang, Xiaoli Ke, Maixin Lu. Nile tilapia TBK1 interacts with STING and TRAF3 and is involved in the IFN-β pathway in the immune response. Fish and Shellfish Immunology 142 (2023) 109125.通訊作者
8.Fengying Gao, Jicai Pang, Maixin Lu*, Zhigang Liu, Miao Wang, Xiaoli Ke, Mengmeng Yi, Jianmeng Cao.Nile tilapia TLR3 recruits MyD88 and TRIF as adaptors and is involved in the NF-κB pathway in the immune response.International Journal of Biological Macromolecules 218 (2022) 878–890. IF:8.025.第一作者
9.Fengying Gao,Jicai Pang, Maixin Lu, Zhigang Liu, Miao Wang, Xiaoli Ke, Mengmeng Yi, Jianmeng Cao. TLR5 recognizesAeromonas hydrophilaflagellin and interacts with MyD88 in Nile tilapia.Developmental and Comparative Immunology, 2022,133,10409. IF：3.605.第一作者
10.Feng-ying Gao, Xin Zhou, Mai-xin Lu*, Miao Wang, Zhi-gang Liu, Jian-meng Cao, Xiao-li Ke, Meng-meng Yi. Nile tilapia TRIM39 recruits I3K413 and I3KL45 as adaptors and is involved in the NF-κB pathway. Journal of Fish Biology, 2022, 101(1), 144–153 IF:2.504.第一作者
11.Feng-ying Gao,Xin Zhou, Mai-Xin Lu*, Miao Wang, Zhi-Gang Liu, Jian-Meng Cao, Xiao-Li Ke, Meng-Meng Yi, Deng-Gao Qiu.TLR1 in Nile tilapia: The conserved receptor cannot interact with MyD88 and TIRAP but can activate NF-κB in vitro.Developmental and Comparative Immunology, 127 (2022) 104300. IF：3.605.第一作者
12. Xin Zhou,Fengying Gao*, Maixin Lu*, Zhigang Liu, Miao Wang, Jianmeng Cao, Xiaoli Ke, Mengmeng Yi. DDX43 recruits TRIF or IPS-1 as an adaptor and activates the IFN-β pathway in Nile tilapia (Oreochromis niloticus).Molecular Immunology 143 (2022) 7–16.IF：4.174.通訊作者.
13.Fengying Gao, Jie Liu, Maixin Lu*, Zhigang Liu, Miao Wang, Xiaoli Ke, Mengmeng Yi, Jianmeng Cao. Nile tilapia Toll-like receptor 7 subfamily Intracellular TLRs that recruit MyD88 as an adaptor and activate the NF-κB pathway in the immune response. Developmental Comparative Immunololgy 2021, 125:104173. IF：3.636.第一作者
14.Gao Feng-ying, Pang Ji-cai, Wang Miao, Lu Mai-xin, Liu Zhi-gang, Cao Jian-meng, Ke Xiao-li, Yi Meng-meng. Structurally diverse genes encode TLR13 in Nile tilapia: The two receptors can recognize Streptococcus 23S RNA and conduct signal transduction through MyD88. Molecular Immunology, 2021, 132,60-78. IF：4.407.第一作者
15. Xueqing Han,Fengying Gao*, Maixin Lu*, Zhigang Liu, Miao Wang, Xiaoli Ke, Mengmeng Yi, Jianmeng Cao. Molecular characterization, expression and functional analysis of IRAK1 and IRAK4 in Nile tilapia (Oreochromis niloticus). Fish & Shellfish Immunology, 2020, 97: 135–145. SCI，IF：3.29.通訊作者
16. Xue-qing Han,Fengying Gao*, Maixin Lu*, Zhig-ang Liu, Miao Wang, Xiao-li Ke, Yan-xia Gao. Identification and characterization of tumor necrosis factor receptor (TNFR)-associated factor 3 from Nile tilapia,Oreochromis niloticus. Journal of fish biology, 2020, 96(1):185-193. SCI，IF：2.04 .通訊作者
17.Feng-Ying Gao,Dong Zhang, Mai-Xin Lu*, Jian-Meng Cao, Zhi-Gang Liu, Xiao-Li Ke, Miao Wang, De-Feng Zhang. MHC Class IIB gene polymorphisms associated with resistance/susceptibility to Streptococcus agalactiae in Nile tilapiaOreochromis niloticus. DISEASES OF AQUATIC ORGANISMS, 2019, 133: 253–261. IF=1.659，第一作者
18.Feng-Ying Gao,Dong Zhang, Mai-Xin Lu*, Jian-Meng Cao, Zhi-Gang Liu, Xiao-Li Ke, Miao Wang, De-Feng Zhang, Meng-Meng Yi. MHC class IIA polymorphisms and their association with resistance-susceptibility toStreptococcus agalactiaein Nile tilapia,Oreochromis niloticus. Journal of Fish Biology. 2018; 93:1207-1215. SCI，IF：1.79.第一作者
19.Feng-Ying Gao,Mai-Xin Lu*, Miao Wang, Zhi-Gang Liu, Xiao-Li Ke, De-Feng Zhang, Jian-Meng Cao. Molecular characterization and function analysis of three RIG-I-like receptor signaling pathway genes (MDA5, LGP2 and MAVS) inOreochromis niloticus. Fish and Shellfish Immunology 82 (2018) 101–114. SCI, IF:3.18,第一作者
20.Feng-ying Gao,Ji-cai Pang, Mai-xin Lu*, Xian-le Yang*, Hua-ping Zhu, Xiao-li Ke, Zhi-gang Liu, Jian-meng Cao, Miao Wang. Molecular characterization, expression and functional analysis of NOD1, NOD2 and NLRC3 in Nile tilapia (Oreochromis niloticus). Fish & Shellfish Immunology, 2018,73:207-219. SCI, IF:3.18第一作者
21. Ji-cai Pang1,Feng-ying Gao1, Mai-xin Lu*, Xing Ye, Hua-ping Zhu, Xiao-li Ke. Major histocompatibility complex class IIA and IIB genes of Nile tilapiaOreochromis niloticus: Genomic structure, molecular polymorphism and expression patterns. Fish & Shellfish Immunology, 2013, 34 (2):486-496，SCI, IF:3.32,共同第一作者
