
歐密,女,1990年生,博士,副研究員,碩士生導師,中國水產科學研究院鱧和草魚遺傳育種創新團隊副首席。入選中國水產科學研究院“百名科技英才”和“水科英才”拔尖人才,擔任中國水產學會青年工作委員會委員。主要從事特色淡水養殖魚類遺傳育種與生殖發育研究。先后主持國家自然科學基金面上項目、青年項目、廣東省自然科學基金青年提升項目、面上項目等各類項目20余項。以第一/通訊作者(含共同)在Gigascience、Aquaculture等發表學術論文24篇(SCI 18篇,中文核心5篇);授權發明專利9件(第一發明人1件,并轉化);發布水產行業標準2項(第一完成人1項)、地方標準1項;作為技術骨干參與培育水產新品種—雜交鱧“雄鱧1號”(GS-02-003-2022)(第三完成人);先后獲2023中國農業農村重大科技新成果—新產品類等5項科技獎項。
聯系方式:
(1)電話:020-81174522;13925738649
(2)郵箱:om1990@www.188233.com
(3)通訊地址:廣州市荔灣區芳村西塱興漁路1號
研究方向:特色淡水養殖魚類遺傳育種與生殖發育
主持的重點項目(僅列重大項目5項):
1. 國家自然科學基金-面上項目:斑鱧性別決定基因定位與功能鑒定及性別決定機制研究(32373127),2024.01-2027.12,50萬元。
2. 國家自然科學基金-青年基金項目:Amh基因在斑鱧性別分化和性腺發育的功能研究(31902351),2020.01-2022.12,21萬元。
3. 廣東省自然科學基金-青年提升項目:基于原始生殖細胞調控的性控技術研發與全雄斑鱧新種質創制2024.01-2026.12,30萬元。
4. 廣東省自然科學基金-面上項目:斑鱧兩種芳香化酶Cyp19a1a和Cyp19a1b的表達和功能研究(2021A1515012075),2021.01-2023.12,10萬元。
5. 2023年高水平廣東省農業科技示范市建設資金項目:雜交鱧“雄鱧1號”新品種示范推廣,2024.01-2024.12,20萬元。
代表論文與著作(限第1作者及通訊作者):
1. Zhang XT, Wu YX, Zhang Y, Zhang J, Chu PF, Chen KC, Liu HY, Luo Q, Fei SZ, Zhao J*, Ou M*. Histological observations and transcriptome analyses reveal the dynamic changes in the gonads of the blotched snakehead (Channa maculata) during sex differentiation and gametogenesis. Biology of Sex Differences, 2024, 15: 70.
2. Liu HY, Zhang J, Cui TX, Xia WW, Luo Q, Fei SZ, Zhu XP, Chen KC, Zhao J*, Ou M*. Genome-wide association studies (GWAS) and transcriptome analysis reveal male heterogametic sex-determining regions and candidate genes in northern snakeheads (Channa argus). International Journal of Molecular Sciences, 2024, 25: 10889.
3. Zhang Y, Lu YT, Xu F, Zhang XT, Wu YX, Zhao J, Luo Q, Liu HY, Chen KC, Fei SZ, Cui XJ, Sun YD*, Ou M*. Molecular characterization, expression pattern, DNA methylation and gene disruption of Figla in Blotched snakehead (Channa maculata). Animals, 2024, 14: 491.
4. Liu HY, Cui TX, Liu HJ, Zhang J, Luo Q, Fei SZ, Chen KC, Zhu XP, Zhu CK, Li BJ, Fang LZ, Zhao J*, Ou M*. Chromosome-level genome assembly of the mud carp (Cirrhinus molitorella) using PacBio HiFi and Hi-C sequencing. Scientific Data, 2024, 11: 1249.
5. Zhang XT, Wu YX, Zhang Y, Zhang J, Chen KC, Liu HY, Luo Q, Luo Q, Zhao J*, Ou M*. Molecular characteristics, expression patterns, and response of insulin-like growth factors gene induced by sex steroid hormones in blotched snakehead (Channa maculata). Fishes, 2024, 9: 120.
6. Zhang Y, Shi JY, Lu YT, Luo Q, Chu PF, Huang R, Chen KC, Zhao J, Wang YP*, Ou M*. Molecular cloning and characterization of scavenger receptor class b type 1 in grass carp (Ctenopharyngodon idellus) and its expression profile following grass carp reovirus challenge. Fishes, 2024, 9: 276.
7. Ou M, Wang F, Li KB, Wu YX, Huang SJ, Luo Q, Liu HY, Zhang XC, Fei SZ, Chen KC*, Zhao J*. Generation of myostatin gene-edited blotched snakehead (Channa maculata) using CRISPR/Cas9 system. Aquaculture, 2023, 563(1): 738988.
8. Huang SJ, Wu YX, Chen KC, Zhang XT, Zhao J, Luo Q, Liu HY, Wang F, Li KB, Fei SZ, Zhang XC, Ou M*. Gene expression and epigenetic modification of aromatase during sex reversal and gonadal development in blotched snakehead (Channa maculata). Fishes, 2023, 8(3): 129.
9. Ou M, Chen KC, Gao DD, Wu YD, Luo Q, Liu HY, Zhao J*. Characterization, expression and CpG methylation analysis of Dmrt1 and its response to steroid hormone in blotched snakehead (Channa maculata). Comparative Biochemistry and Physiology - Part B, 2022, 257: 110672.
10. Ou M, Huang R, Yang C, Gui B, Luo Q, Zhao J, Li YM, Liao LJ, Zhu ZY, Wang YP*, Chen KC*. Chromosome-level genome assemblies of Channa argus and Channa maculata and comparative analysis of their temperature adaptability. Gigascience, 2021, 10: 1-11.
11. Ou M, Chen KC, Luo Q, Liu HY, Wang YP, Chen BX, Liang XQ, Zhao J*. Performance evaluation of XY all-male hybrids derived from XX female Channa argus and YY super-males Channa maculata. Aquaculture Reports, 2021, 20: 100768.
12. Ou M, Chen KC, Gao DD, Wu YD, Chen Z, Luo Q, Liu HY, Zhao J*. Comparative transcriptome analysis on four types of gonadal tissues of blotched snakehead (Channa maculata). Comparative Biochemistry and Physiology - Part D, 2020, 35: 100708.
13. Luo Q#, Ou M#, Zhao J, Liu HY, Gao DD, Wu YD, Zhang LL, Chen KC*. Expression profile and estrogenic regulation of Amh during gonadal sex differentiation in northern snakehead (Channa argus). Genes & Genomics, 2020, 42: 827-835.
14. Ou M, Mao HH, Luo Q, Zhao J, Liu HY, Zhu XP, Chen KC*, Xu HY*. The DNA methylation level is associated with the superior growth of the hybrid fry in snakehead fish (Channa argus?×?Channa maculata). Gene, 2019, 703: 125-133.
15. Ou M, Huang R, Luo Q, Xiong L, Chen KC*, Wang YP*. Characterisation of scavenger receptor class B type 1 in rare minnow (Gobiocypris rarus). Fish and Shellfish Immunology, 2019, 87: 614-622.
16. Ou M, Zhao J, Luo Q, Hong XY, Zhu XP, Liu HY, Chen KC*. Characteristics of hybrids derived from Channa argus ♀?×?Channa maculata ♂. Aquaculture, 2018, 492: 349-356.
17. Ou M, Yang C, Luo Q, Huang R, Zhang AD, Liao LJ, Li YM, He LB, Zhu ZY, Wang YP*. An NGS-based approach for the identification of sex-specific markers in snakehead (Channa argus). Oncotarget, 2017, 8(58): 98733-98744.
18. Ou M, Huang R, Xiong L, Luo LF, Chen G, Liao LJ, Li YM, He LB, Zhu ZY, Wang YP*. Molecular cloning of the MARCH family in grass carp (Ctenopharyngodon idella) and their response to grass carp reovirus challenge. Fish and Shellfish Immunology, 2017, 87: 614-622.
19. 吳玉霞, 張嘯天, 張揚, 趙建, 羅青, 劉海洋, 費樹站, 陳昆慈, 歐密*. 斑鱧ghr基因克隆、表達分析及性類固醇激素誘導的響應. 農業生物技術學報, 2024, 32(6): 1371-1384.
20. 黃蘇靜, 吳玉霞, 夏威威, 張嘯天, 趙建, 李凱彬, 羅青, 劉海洋, 費樹站, 陳昆慈, 歐密*. 烏鱧三種性腺組織的轉錄組比較分析. 農業生物技術學報, 2024, 32(2): 379-395.
21. 歐密, 徐晟云, 陳昆慈, 羅青, 劉海洋, 梁新球, 趙建*. 乳酸菌對雜交鱧腸道菌群和生長的影響. 農業生物技術學報, 2022, 30(1): 138-150.
22. 歐密, 趙建, 羅青, 劉海洋, 黃容, 汪亞平, 陳昆慈*. 鱧性別控制育種及應用研究進展. 中國農業科技導報, 2022, 24(2): 11-25.
23. 田雨蘇, 孫遠東*, 歐密*, 劉雨芳, 崔小娟, 周定港, 車文安. 初探壬基酚致紅鯽發育畸形的機制. 水產學報, 2020, 44(8): 1-18.
24. 歐密, 趙建, 劉海洋, 夏威威, 羅青, 張新鋮, 陳昆慈, 費樹站. 鑒定鱧的引物組合、微衛星標記組合、多重PCR體系及其方法和應用. 發明專利: ZL202211728879.2. 授權公告日: 2023.09.05.
25. 歐密, 趙建, 王建波, 陳昆慈, 羅青, 劉海洋, 鄭光明, 尹怡, 尹建雄, 陳柏湘. 行業標準: SC/T 1174-2023 烏鱧人工繁育技術規范.